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Study identifier: NCT06602635 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Hybrid Score to Predict OTVA-SOO in Patients with Wide Basal QRS

Condition: ECG · Ventricular Arrhythmias · Catheter Ablation  ·  Sponsor: Centro Medico Teknon

PhaseN/A
Planned participants100
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Outflow tract ventricular arrhythmia (OTVA) is the most common type of ventricular arrhythmia, and catheter ablation (CA) is the primary treatment option for patients experiencing symptoms. Accurately identifying the origin site of OTVA is essential for effective catheter ablation, minimizing procedural risks, and enhancing treatment success. However, most studies that developed algorithms or scoring systems for distinguishing OTVA origins excluded participants with structural heart disease and those with paced rhythms from their study groups. A recent prospective evaluation of a hybrid score (HS) that integrates both clinical and ECG data to predict OTVA-SOO, including patients with cardiac implantable electronic devices and those with structural heart disease in our study. The presented study aimed to assess the effectiveness of the previously described hybrid algorithm in predicting OTVA-SOO in a patient population characterized by a wide basal QRS due to intraventricular conduction defects or paced rhythms. The Hybrid Score The Hybrid Score (HS), involves a sum of points based on clinical and ECG characteristics. Points are assigned as follows: one point each for being over 50 years old, male, and having arterial hypertension. ECG-based points are allocated according to QRS transition: 3 points for a transition in V1, 2 points for V2, 1 point for V3 if the R-wave in V3 is greater than 1 mV; 1 point is subtracted if V3 has an R-wave less than 1 mV, and further deductions…

This description comes directly from the study's public registry record.

Talk to the study team

Antonio Berruezo, MD, PhD  ·  3384090290  ·  antonio.berruezo@quironsalud.es

Always discuss trial participation with your own doctor first.

Locations (6)

Vrije Universiteit BrusselBrussels, Belgium, BelgiumRecruiting
Maria Cecilia HospitalCotignola, Italy, ItalyRecruiting
Niguarda Ca Granda HospitalMilan, Italy, ItalyRecruiting
Cisanello University Hospital (Pisa, Italy)Pisa, Italy, ItalyRecruiting
Teknon Medical CenterBarcelona, Spain, SpainRecruiting
Hospital Universitario Puerta del MarCadiz, Spain, SpainRecruiting

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Source record: clinicaltrials.gov/study/NCT06602635