Condition: Brain Tumor, Pediatric · Sponsor: Institut Claudius Regaud
This is a prospective, open-label, multicentric study designed to correlate the dose delivered to the hippocampus with declarative memory deficits 2 years after radiotherapy treatment in a paediatric population who had received brain irradiation between the ages of 4 and 12 for a brain tumour. In order to meet this objective, several neuropsychological assessments consisting of parental questionnaires and cognitive tests will be carried out during the course of the study, at the following two stages: * A 1st assessment at patient inclusion, i.e. 2 years after the end of radiotherapy treatment, * And a second assessment 2 years after patient inclusion, i.e. 4 years after the end of radiotherapy treatment. A retrospective assessment of the patient's neurocognitive level 1 year before the diagnosis of the disease will also be carried out at inclusion, with the parents completing a questionnaire specifically designed for the trial. In addition, patients who have received their radiotherapy treatment at the IUCT-O will be offered participation in the ancillary imaging study. If the parents and the patient agree, multimodal MRI scans specific to the study (without injection of contrast) will be performed at inclusion and 2 years after inclusion. Imaging and radiotherapy data will be collected in parallel using the PediaRT software used in current practice (collection of radiotherapy dosimetric data as well as standard MRI examinations pre-operatively, post-operatively, and at …
This description comes directly from the study's public registry record.
Anne LAPRIE · 05 31 15 54 43 · laprie.anne@iuct-oncopole.fr
Always discuss trial participation with your own doctor first.
| CHU Angers | Angers, France | Recruiting |
| CHU de Bordeaux | Bordeaux, France | Recruiting |
| Centre François Baclesse | Caen, France | Recruiting |
| Centre Georges François Leclerc | Dijon, France | Not Yet Recruiting |
| Centre Oscar Lambret | Lille, France | Not Yet Recruiting |
| Centre Léon Bérard | Lyon, France | Recruiting |
| APHM - Hôpital la Timone | Marseille, France | Not Yet Recruiting |
| Institut du Cancer de Montpellier | Montpellier, France | Not Yet Recruiting |
| Institut Curie | Paris, France | Not Yet Recruiting |
| Centre Eugène Marquis | Rennes, France | Not Yet Recruiting |
| Institut de Cancérologie de l'Ouest | Saint-Herblain, France | Not Yet Recruiting |
| Centre Paul Strauss | Strasbourg, France | Recruiting |
+ 3 more locations — full list on the registry record.
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT06599879