Condition: Solid Tumor, Adult · Colorectal Cancer · Pancreatic Ductal Adenocarcinoma · Sponsor: Crossignal Therapeutics, Inc.
This is an FIH, multicenter, open-label, dose escalation and dose expansion/dose optimization study of CT3001, which will be conducted in 2 phases: Phase 1 and Phase 2b. Phase 1 will be a standard 3+3 dose escalation and dose finding study in patients with advanced solid tumors for whom there is no available therapy (or patients are not candidates for such therapy) for the assessment of DLTs at up to 7 dose levels of CT3001. Phase 2b is a dose finding/dose optimization study of CT3001 in combination with SOC chemotherapy (FOLFOX) to evaluate the safety and preliminary efficacy of CT3001 in patients with advanced CRC who are eligible for re-engaging FOLFOX-based chemotherapy.
This description comes directly from the study's public registry record.
Can Zhang · 413-932-9263 · czhang@crossignaltherapeutics.com
Always discuss trial participation with your own doctor first.
| MD Anderson Cancer Center | Houston, Texas, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06598007