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Study identifier: NCT06597565 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Phase II Study of ACR-368 and Low Dose Gemcitabine in R/M HNSCC

Condition: Head and Neck Squamous Cell Carcinoma  ·  Sponsor: H. Lee Moffitt Cancer Center and Research Institute

PhasePhase 2
Planned participants43
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of the study is to determine the activity and safety of ACR-368 (prexasertib) in combination with gemcitabine in participants with Head and Neck Squamous Cell Carcinoma (HNSCC). Participants will receive the study drugs ACR-368 and a low dose of gemcitabine once every 2 weeks in 4-week cycles and will continue on treatment unless the disease deteriorates.

This description comes directly from the study's public registry record.

Talk to the study team

Kara Hoffman  ·  813-745-6020  ·  kara.hoffman@moffitt.org

Always discuss trial participation with your own doctor first.

Locations (1)

Moffitt Cancer CenterTampa, Florida, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06597565