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Study identifier: NCT06596694 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study of Patritumab Deruxtecan in Participants With Gastrointestinal Cancers (MK-1022-011) (HERTHENA-PanTumor02)

Condition: Gastrointestinal Cancer  ·  Sponsor: Merck Sharp & Dohme LLC

PhasePhase 1/Phase 2
Planned participants180
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Researchers want to learn if patritumab deruxtecan (MK-1022) can treat certain gastrointestinal (GI) cancers. The GI cancers being studied are advanced (the cancer has spread to other parts of the body). The goals of this study are to learn: * About the safety and how well people tolerate of patritumab deruxtecan * How many people have the cancer respond (get smaller or go away) to treatment

This description comes directly from the study's public registry record.

Talk to the study team

Toll Free Number  ·  1-888-577-8839  ·  Trialsites@msd.com

Always discuss trial participation with your own doctor first.

Locations (62)

UCLA Hematology Oncology Santa Monica ( Site 1205)Santa Monica, California, United StatesActive Not Recruiting
University of Colorado Cancer Center ( Site 1200)Aurora, Colorado, United StatesRecruiting
Sibley Memorial Hospital ( Site 1208)Washington D.C., District of Columbia, United StatesRecruiting
University of Florida ( Site 1202)Gainesville, Florida, United StatesRecruiting
Mount Sinai Medical Center Comprehensive Cancer Center ( Site 1213)Miami Beach, Florida, United StatesRecruiting
Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital-Research ( Site 1203)Marietta, Georgia, United StatesCompleted
University of Chicago Medical Center ( Site 1204)Chicago, Illinois, United StatesRecruiting
Renown Regional Medical Center ( Site 1221)Reno, Nevada, United StatesActive Not Recruiting
NYU Langone Hospital - Long Island ( Site 1230)Mineola, New York, United StatesCompleted
Perlmutter NYU Cancer Center ( Site 1212)New York, New York, United StatesCompleted
Scott & White Medical Center-Temple ( Site 1224)Temple, Texas, United StatesRecruiting
Oncology and Hematology Associates of Southwest Virginia (BRCC) ( Site 1207)Roanoke, Virginia, United StatesRecruiting

+ 50 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06596694