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Study identifier: NCT06595953 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Gaze-Contingent Music Therapy Augmentation of CBT for Pediatric Anxiety

Condition: Psychiatric Disorders · Anxiety Disorders  ·  Sponsor: National Institute of Mental Health (NIMH)

PhasePhase 2
Planned participants150
Who can joinAll sexes, 8 Years to 17 Years
Healthy volunteersNo

About this study

Background: Anxiety disorders are becoming more common among children and teenagers. Anxiety can lead to long-term physical and mental problems, such as depression. Treatments for anxiety disorders include medications as well as cognitive behavioral therapy (CBT); CBT is a form of talking therapy. Both approaches work in only about 50 percent of cases. A new approach, called gaze-contingent music reward therapy (GCMRT), may help. Objective: To find out whether GCMRT combined with CBT is more effective than CBT alone. Eligibility: Children aged 8 to 17 years with separation anxiety disorder; generalized anxiety disorder; or social anxiety disorder. They must be enrolled in protocol 01-M-0192. Design: Participants will come to the clinic once a week for 4 weeks for CBT. Sometimes the participant will meet with the doctor alone; sometimes their parent may be present. They will do some computer-based tasks: They may be asked to push a button when a target appears; they may look at pictures of faces while the computer tracks their eye movements. Participants will take questionnaires each week. They will answer questions about their anxiety symptoms, feelings, and behavior. For the next 8 weeks, participants will participate in both CBT and 1 of 2 types of GCMRT. GCMRT is a computer-based task. Participants will look at pictures with many faces in them; while they do this, pleasant music will play and stop playing over a 12-minute period. Participants will have a final vi…

This description comes directly from the study's public registry record.

Talk to the study team

Daniel S Pine, M.D.  ·  (301) 594-1318  ·  daniel.pine@nih.gov

Always discuss trial participation with your own doctor first.

Locations (1)

National Institutes of Health Clinical CenterBethesda, Maryland, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06595953