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Study identifier: NCT06595459 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The Options 2 Study

Condition: Smoker · Smoking Cessation  ·  Sponsor: University of Wisconsin, Madison

PhasePhase 4
Planned participants300
Who can joinAll sexes, 21 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to investigate how well nicotine pouches and nicotine mini lozenges serve as substitutes for cigarettes when people try to switch from smoking to using these alternate nicotine products. Participants will: * Use nicotine pouches, nicotine mini lozenges, or no study product for a week and then try not to smoke for 3 weeks. * Have 6 in-person research visits and 1 follow-up call * Complete questionnaires at each study contact and use a smartphone app to record smoking and study product use

This description comes directly from the study's public registry record.

Talk to the study team

Megan Piper, PhD  ·  608-265-5472  ·  mep@ctri.wisc.edu

Mark Zehner  ·  608-262-7568  ·  mark.zehner@wisc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of WisconsinMadison, Wisconsin, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06595459