Condition: ALS · FTD · Sponsor: Azienda Ospedaliero-Universitaria di Modena
The goal of this study is to learn from discordant twins affected by Amyotrophic Lateral Sclerosis and/or Frontotemporal Dementia the contribution of genetic background versus environmental exposure. The main questions it aims to answer is: * How far does the genetic background explain the onset of ALS/FTD in discordant twins? * Which environmental factors and events occurring in post-fetal life influence the onset or progression of this neurodegenerative condition? Participants with ALS and/or FTD with a monozygotic or dizygotic twin willing to contribute to this research will be followed up for two years by specialized Motor Neuron Disorders centers in Italy, donating biological specimen for -omic sciences analysis, and checking out if prodromal signs/symptoms of these two conditions will develop during time.
This description comes directly from the study's public registry record.
Jessica Mandrioli, MD, Prof · 0593961640 · jessica.mandrioli@unimore.it
Cecilia Simonini, BSc · 0593961640 · ceciliasimonini24@gmail.com
Always discuss trial participation with your own doctor first.
| Azienda Ospedaliero-Universitaria di Modena | Modena, Italy, Italy | Recruiting |
| Azienda Ospedaliero-Universitaria Policlinico P. Giaccone di Palermo | Palermo, Italy, Italy | Recruiting |
| Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino | Torino, Italy, Italy | Recruiting |
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT06595212