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Study identifier: NCT06592820 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Endoscopic Ultrasound Shear Wave Elastography Study

Condition: MASLD · MASH · Fibrosis, Liver  ·  Sponsor: Olympus Corporation of the Americas

PhaseN/A
Planned participants300
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study shall be a prospective, multicenter, single arm, consecutive, interventional study conducted in a post-market setting using commercially available devices. Consecutive, eligible patients with clinical suspicion of MASLD or MASH reporting for an endoscopic ultrasound and liver biopsy for evaluation of fibrosis will be enrolled. EUS Shear Wave Elastography and Attenuation Imaging technologies will be compared to liver biopsy and FibroScan results and other non-invasive fibrosis screening modalities . The data collected during this study will be evaluated in accordance with the procedures set forth in the protocol. The main question\[s\] it aims to answer are: * Establish optimal cutoffs for EUS-SWE in reference to liver biopsies staging system for liver fibrosis * Evaluate the diagnostic performance of EUS-SWE compared to FibroScan (VCTE) and to other non-invasive fibrosis screening modalities (screening scores). Participants will undergo: * Endoscopic Ultrasound with Shear Wave Elastography (SWE) and Attenuation Imaging (ATI) * Liver biopsy * FibroScan

This description comes directly from the study's public registry record.

Talk to the study team

Octavia Plingu  ·  4089413623  ·  octavia.plingu@olympus.com

Jewel Gill  ·  9196333967  ·  Jewel.Gill@olympus.com

Always discuss trial participation with your own doctor first.

Locations (2)

Brigham and Women's HospitalBoston, Massachusetts, United StatesRecruiting
Geisinger Medical CenterDanville, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06592820