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Study identifier: NCT06591793 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study of Subretinally Injected AAVB-081 in Patients With Usher Syndrome Type IB (USH1B) Retinitis Pigmentosa

Condition: Usher Syndrome, Type 1B  ·  Sponsor: AAVantgarde Bio Srl

PhasePhase 1/Phase 2
Planned participants15
Who can joinAll sexes, 18 Years to 50 Years
Healthy volunteersNo

About this study

The purpose of the 081-101 study is to evaluate the safety and tolerability of a single subretinal injection of AAVB-081 in USH1B patients with retinitis pigmentosa due to a mutation in the MYO7A gene. The study will also assess the initial efficacy following AAVB-081 administration.

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Operations Manager  ·  +448000465680  ·  clinicaltrials@aavantgarde.com

Always discuss trial participation with your own doctor first.

Locations (3)

University of Campania Luigi VanvitelliNaples, ItalyRecruiting
Moorfields Eye HospitalLondon, United KingdomRecruiting
Retina Clinic LondonLondon, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT06591793