Condition: Gastric Intestinal Metaplasia · Gastric Precancer · Sponsor: Katherine Garman
This study is designed to test the use of Pyrvinium vs placebo as a treatment for gastric intestinal metaplasia with features associated with increased risk of cancer. Response will be determined by assessing the extent and quality of the gastric intestinal metaplasia before and after treatment. A secondary aim will be to generate gastric organoids from patient-derived samples to test the effects of pyrvinium in vitro in patient-derived samples, and also to identify new drugs that may help reverse gastric intestinal metaplasia.
This description comes directly from the study's public registry record.
Nicole Pavlus · 919-684-0311 · nicole.pavlus@duke.edu
Laura Hayes, MS · 919-684-8771 · laura.hayes@duke.edu
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| Duke Health | Durham, North Carolina, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06590454