Condition: Chronic Lymphocytic Leukemia · Small Lymphocytic Lymphoma · Sponsor: Loxo Oncology, Inc.
The main purpose of Part 1 of this study is to assess the efficacy and safety of 3 dose levels of Pirtobrutinib in participants with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL), who have received 1-3 lines of treatment including a covalent Bruton tyrosine kinase (BTK) inhibitor. The purpose of Part 2 of this study is to evaluate pirtobrutinib monotherapy in participants with treatment-naïve CLL/SLL with 17p deletions. Participation in Part 1 is expected to last approximately 3 years. Participation in Part 2 is expected to last up to 2 years.
This description comes directly from the study's public registry record.
Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or · 1-317-615-4559 · LillyTrials@Lilly.com
Physicians interested in becoming principal investigators please contact · clinical_inquiry_hub@lilly.com
Always discuss trial participation with your own doctor first.
| Ironwood Cancer & Research Centers | Chandler, Arizona, United States | Recruiting |
| City of Hope National Medical Center | Duarte, California, United States | Recruiting |
| City of Hope National Medical Center | Irvine, California, United States | Recruiting |
| Palo Alto Medical Foundation Research Institute (PAMFRI) | Palo Alto, California, United States | Recruiting |
| Stanford Cancer Center | Palo Alto, California, United States | Recruiting |
| Rocky Mountain Cancer Center | Aurora, Colorado, United States | Recruiting |
| University of Miami Hospital and Clinics, Sylvester Cancer Center | Miami, Florida, United States | Recruiting |
| City of Hope National Medical Center, Atlanta Cancer Center | Newnan, Georgia, United States | Recruiting |
| Mission Cancer + Blood | Waukee, Iowa, United States | Recruiting |
| Saint Elizabeth Medical Center Edgewood | Edgewood, Kentucky, United States | Recruiting |
| American Oncology Partners, PA | Bethesda, Maryland, United States | Recruiting |
| Boston Medical Center | Boston, Massachusetts, United States | Recruiting |
+ 119 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06588478