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Study identifier: NCT06586515 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

Condition: Pancreatic Ductal Adenocarcinoma · Non-small Cell Lung Cancer · Colorectal Cancer  ·  Sponsor: Eli Lilly and Company

PhasePhase 1
Planned participants630
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The main purpose of this study is to assess safety \& tolerability and antitumor activity of LY3962673 as monotherapy and in combination with other chemotherapy agents in participants with KRAS G12D-mutant advanced solid tumor types. The study is expected to last approximately 5 years.

This description comes directly from the study's public registry record.

Talk to the study team

Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or  ·  1-317-615-4559  ·  LillyTrials@Lilly.com

Physicians interested in becoming principal investigators please contact  ·  clinical_inquiry_hub@lilly.com

Always discuss trial participation with your own doctor first.

Locations (52)

City of HopeDuarte, California, United StatesRecruiting
University of California, Los Angeles (UCLA)Santa Monica, California, United StatesRecruiting
Sarah Cannon Research Institute at HealthOneDenver, Colorado, United StatesRecruiting
Sibley Memorial HospitalWashington D.C., District of Columbia, United StatesRecruiting
Florida Cancer Specialists - Lake Nona - Sarah Cannon Research InstituteOrlando, Florida, United StatesRecruiting
Emory University School of MedicineAtlanta, Georgia, United StatesRecruiting
Community Health NetworkIndianapolis, Indiana, United StatesRecruiting
Massachusetts General HospitalBoston, Massachusetts, United StatesNot Yet Recruiting
Dana-Farber Cancer InstituteBoston, Massachusetts, United StatesRecruiting
Barbara Ann Karmanos Cancer InstituteDetroit, Michigan, United StatesRecruiting
South Texas Accelerated Research Therapeutics (START) MidwestGrand Rapids, Michigan, United StatesRecruiting
New York University (NYU) Langone Medical CenterNew York, New York, United StatesRecruiting

+ 40 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06586515