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Study identifier: NCT06586281 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Elucidating Shared Mechanisms Contributing to NAFLD and PsA Disease Severity With Guselkumab Therapy

Condition: Psoriatic Arthritis  ·  Sponsor: University of California, San Diego

PhaseNA
Planned participants20
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

While many studies examine Nonalcoholic fatty liver disease (NAFLD), little is known about its progression to high-risk nonalcoholic steatohepatitis (NASH) in PsA patients. Shared disease mechanisms may explain the increased severity in PsA. This study involves two visits from PsA patients with NAFLD and active disease signs (e.g., swollen joint, enthesitis, or psoriatic plaque). It aims to assess the impact of biological therapies on liver disorders, joints, and skin in PsA patients.

This description comes directly from the study's public registry record.

Talk to the study team

Monica Guma  ·  8588226523  ·  mguma@health.ucsd.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of California, San DiegoSan Diego, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06586281