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Study identifier: NCT06586203 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Clinical Utility of a Genomic Predictor Test on the Management of Cardiorenal Complications of Type 2 Diabetes

Condition: Diabetes Mellitus, Type 2 · Cardiovascular Diseases · Diabetic Nephropathy Type 2  ·  Sponsor: Optithera

PhaseNA
Planned participants2714
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this pragmatic trial is to provide Real World Evidence (RWE) on the impact of the result of a polygenic risk prediction test of cardiorenal complications of T2D, so that more patients at high risk of these complications achieve over an 18 months period, recommended therapeutic targets. This will be demonstrated as a significant improvement in a composite value including HbA1c or systolic blood pressure (SBP) or albuminuria (UACR), or glomerular filtration rate (GFR) lowering. Researchers will compare the recommended therapeutic targets of uninformed and informed patients to see if the knowledge of the risk by the patients and their treating physicians improves achievement of these targets. Participants will: Have a saliva sampling to determine the genetic risk. Visit the clinic once every 3 months for checkups and tests Answer two questionnaires on quality of life.

This description comes directly from the study's public registry record.

Talk to the study team

Marie-Renée Guertin, il,cra  ·  514-249-4209  ·  marie-renee.guertin.chum@ssss.gouv.qc.ca

Johanne Tremblay, PhD  ·  514-890-8247  ·  johanne@optithera.onmicrosoft.com

Always discuss trial participation with your own doctor first.

Locations (2)

CHUMMontreal, Quebec, CanadaRecruiting
ELNA MedicalMontreal, Quebec, CanadaNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06586203