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Study identifier: NCT06585787 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

Condition: Alzheimer Disease  ·  Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

PhasePhase 3
Planned participants406
Who can joinAll sexes, 55 Years to 90 Years
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the safety and efficacy of KarXT in adult participants with mild to severe Alzheimer's Disease (AD) with moderate to severe psychosis related to AD.

This description comes directly from the study's public registry record.

Talk to the study team

BMS Clinical Trials Contact Center www.BMSClinicalTrials.com  ·  855-907-3286  ·  Clinical.Trials@bms.com

First line of the email MUST contain NCT # and Site #.

Always discuss trial participation with your own doctor first.

Locations (292)

Local Institution - 1227Chandler, Arizona, United StatesCompleted
Gilbert Neurology Partners - PLLC - AvacareGilbert, Arizona, United StatesRecruiting
Banner Alzheimer's InstitutePhoenix, Arizona, United StatesRecruiting
Local Institution - 1220Scottsdale, Arizona, United StatesCompleted
Advanced Research Center, Inc.Anaheim, California, United StatesRecruiting
Inland Psychiatric Medical Group (IPMG)-ChinoChino, California, United StatesRecruiting
Local Institution - 1230Long Beach, California, United StatesCompleted
USC - The Memory and Aging Center (MAC) - Alzheimer Disease Research Center (ADRC)Los Angeles, California, United StatesRecruiting
Local Institution - 1219Los Angeles, California, United StatesWithdrawn
Local Institution - 1001Orange, California, United StatesCompleted
Local Institution - 1228Orange, California, United StatesCompleted
Local Institution - 1043Pasadena, California, United StatesActive Not Recruiting

+ 280 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06585787