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Study identifier: NCT06582745 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Targeted Approach to Langerhans Cell Histiocytosis (LCH) Using MEK Inhibitor, Trametinib

Condition: Langerhans Cell Histiocytosis  ·  Sponsor: Cook Children's Health Care System

PhasePhase 2
Planned participants75
Who can joinAll sexes, 1 Year to 30 Years
Healthy volunteersNo

About this study

The purpose of this Phase II clinical trial is to establish the safety and effectiveness of trametinib, a targeted therapy, for the treatment of newly or recently diagnosed Langerhans Cell Histiocytosis (LCH) among pediatric patients.

This description comes directly from the study's public registry record.

Talk to the study team

Megan Gibbs, BSN, RN  ·  (682) 885-2116  ·  megan.gibbs@cookchildrens.org

Angelica Gonzalez, PhD  ·  (682) 3033120  ·  angelica.gonzalez@cookchildrens.org

Always discuss trial participation with your own doctor first.

Locations (1)

Cook Children's Health Care SystemFort Worth, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06582745