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Study identifier: NCT06581562 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Open-label Single-Center Study to Evaluate the Safety and Efficacy of Combining Rituximab and AB-101 in B-cell Associated Autoimmune Diseases.

Condition: Rheumatoid Arthritis · Pemphigus Vulgaris · Granulomatosis With Polyangiitis  ·  Sponsor: IRIS Research and Development, LLC

PhasePhase 1
Planned participants30
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study will evaluate the safety and activity of AB-101 in combination with rituximab in B-cell associated autoimmune diseases where rituximab is currently FDA approved (e.g., Rheumatoid Arthritis (RA), Pemphigus Vulgaris (PV), Granulomatosis with polyangiitis (GPA)/microscopic polyangiitis (MPA) as a therapeutic, or is recommended (e.g., in Systemic Lupus Erythematosus (SLE) as a cornerstone for disease management.

This description comes directly from the study's public registry record.

Talk to the study team

Kathy I Perez, M.D.  ·  954-476-2338  ·  kperez@irisrheumatology.com

Jhon Galindo, B.S.  ·  9544762338  ·  jgalindo@irisrheumatology.com

Always discuss trial participation with your own doctor first.

Locations (1)

IRIS Research and Development, LLCPlantation, Florida, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06581562