Condition: Solid Tumours · Sponsor: Boehringer Ingelheim
This is a study for people with advanced cancer for whom previous treatment was not successful. Adults aged 18 and over with advanced cancer with HER2 alterations can join the study. The purpose of this study is to find out whether a medicine called zongertinib helps people with advanced cancers with HER2 alterations. HER2 alterations can cause cancer. Zongertinib inhibits HER2. Participants are put into groups based on the type of advanced cancer they have, the type of HER2 alterations they have, and the dose of zongertinib they receive. Depending on the group they are in, participants take 1 of 2 different doses of zongertinib each day. Participants can continue the treatment as long as they benefit from it and can tolerate it. Participants visit the study site regularly. During many of the visits, the doctors check the size of the tumour and whether it has spread to other parts of the body. During all the visits, the doctors check participants' health and take note of any unwanted effects.
This description comes directly from the study's public registry record.
Boehringer Ingelheim · 1-800-243-0127 · clintriage.rdg@boehringer-ingelheim.com
Always discuss trial participation with your own doctor first.
| Alaska Oncology and Hematology, LLC | Anchorage, Alaska, United States | Recruiting |
| University of Arizona Comprehensive Cancer Center | Tucson, Arizona, United States | Recruiting |
| Precision NextGen Oncology | Beverly Hills, California, United States | Recruiting |
| Scripps Cancer Center Torrey Pines | La Jolla, California, United States | Recruiting |
| Valkyrie Clinical Trials | Los Angeles, California, United States | Recruiting |
| Yale University School of Medicine | New Haven, Connecticut, United States | Recruiting |
| BRCR Global | Tamarac, Florida, United States | Recruiting |
| Illinois Cancer Specialists | Arlington Heights, Illinois, United States | Recruiting |
| Community MD Anderson Cancer Center - East Medical Oncology | Indianapolis, Indiana, United States | Recruiting |
| Maryland Oncology Hematology, Columbia | Columbia, Maryland, United States | Recruiting |
| Karmanos Cancer Institute | Detroit, Michigan, United States | Recruiting |
| Presbyterian Healthcare Services | Albuquerque, New Mexico, United States | Recruiting |
+ 78 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06581432