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Study identifier: NCT06580964 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Heat and Exercise in Aging as Therapy (HEAT)

Condition: Prediabetic State  ·  Sponsor: Texas Tech University

PhaseNA
Planned participants54
Who can joinAll sexes, 50 Years to no upper limit
Healthy volunteersNo

About this study

The main goal of this two-phase clinical trial is to learn whether local heat therapy, using heat pads applied to the legs, can enhance skeletal muscle health, physical function, and blood sugar control in a manner comparable to exercise, specifically High-Intensity Interval Training (HIIT), in older individuals with prediabetes. The study aims to answer the following questions: 1. Does local heat therapy improve muscle architecture (e.g., muscle cross-sectional area, capillary density, mitochondrial content), glucose tolerance, and frailty indicators similarly to HIIT in older individuals with prediabetes? 2. Does local heat therapy as a pre-conditioning method enhance the skeletal muscle response to HIIT in older individuals with prediabetes?

This description comes directly from the study's public registry record.

Talk to the study team

Hui-Ying Luk, PhD  ·  8068340827  ·  huiying.luk@ttu.edu

Danielle Levitt, PhD  ·  8068341830  ·  danielle.levitt@ttu.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Texas Tech UniversityLubbock, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06580964