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Study identifier: NCT06579937 Synced from ClinicalTrials.gov · July 29, 2026
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Effects of Esketamine on Postoperative Behavioral Changes in Children Undergoing Tonsillectomy and/or Adenoidectomy

Condition: Behavior Problem  ·  Sponsor: Fujian Provincial Hospital

PhasePhase 4
Planned participants172
Who can joinAll sexes, 3 Years to 7 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn the effect of intravenous esketamine in postoperative negative behavior changes in children compared to placebo (a look-alike substance that contains no drug). It will also learn about the effect of esketamine in emergence delirium. The main questions are: Dose esketamine lower the incidence of postoperative negative behavior changes compared to placebo? Dose esketamine lower the incidence of emergence delirium compared to placebo? Researchers will compare esketamine to placebo to see if esketamine works to treat postoperative negative behavior change and emergence delirium. Participants will: Receive intravenous esketamine or placebo (a look-alike substance that contains no drug) during anesthesia induction; Fill in the Post hospitalization behavior questionnaire for ambulatory surgery postoperative 1, 7, and 30

This description comes directly from the study's public registry record.

Talk to the study team

Yusheng Yao, MD&PhD  ·  13559939629  ·  fjslyys@fjmu.edu.cn

Sisi Chen, MD  ·  15080109541  ·  chensisi49@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

Fujian Provincial HospitalFuzhou, Fujian, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06579937