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Study identifier: NCT06579755 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of Dengue Tetravalent Vaccine (TDV) in Adults (Age 45 to 60 and >60 to 79 Years)

Condition: Dengue Fever  ·  Sponsor: Takeda

PhasePhase 3
Planned participants800
Who can joinAll sexes, 45 Years to 79 Years
Healthy volunteersYes

About this study

Dengue fever is caused by an infection with the dengue virus. Vaccination with Dengue Tetravalent Vaccine (TDV) can help prevent dengue fever. Researchers have seen that dengue fever now also happens more often in elderly persons. The main aim of this study is to learn more about the side effects of TDV in adult (45 - 60 years) and elderly (60 - 79 years) persons and about TDV's ability to create an immune response in adult and elderly persons. Another aim is to learn about the side effects of TDV in adult and elderly persons in endemic countries who have one or more additional medical conditions (called comorbidities) such as diabetes mellitus, hypertension or a chronic kidney condition. In this study, participants will receive 2 vaccinations with TDV (the second 3 months after the first). During the study, participants will visit their study clinic 5 times.

This description comes directly from the study's public registry record.

Talk to the study team

Takeda Contact  ·  +1-877-825-3327  ·  medinfoUS@takeda.com

Always discuss trial participation with your own doctor first.

Locations (7)

Fundacion Huesped - PPDSBuenos Aires, ArgentinaRecruiting
Associacao Obras Sociais Irma Dulce Hospital Santo AntonioSalvador, Estado de Bahia, BrazilRecruiting
Fundacao Faculdade Regional de Medicina de Sao Jose Do Rio Preto Hospital de Base - PPDSSão José do Rio Preto, São Paulo, BrazilRecruiting
Singapore General Hospital (SGH)Singapore, SingaporeRecruiting
Tan Tock Seng HospitalSingapore, SingaporeRecruiting
Ramathibodi HospitalRatchathewi, Bangkok, ThailandRecruiting
Hospital for Tropical DiseasesRatchathewi, Krung Thep Maha Nakhon-Bangkok, ThailandRecruiting

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Source record: clinicaltrials.gov/study/NCT06579755