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Study identifier: NCT06578507 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Pharmacokinetics, Efficacy and Safety of Twice Daily Dosing Regimen of Hydroxycarbamide Dispersible Tablets in Children With Sickle Cell Disease

Condition: Sickle Cell Disease  ·  Sponsor: Theravia

PhasePhase 2
Planned participants50
Who can joinAll sexes, 9 Months to 11 Years
Healthy volunteersNo

About this study

The purpose of this interventional, phase II, national, multicentric, non-randomised, open-label study is to evaluate the pharmacokinetics (PK), efficacy and safety of Hydroxycarbamide Paediatric dispersible tablets with a twice daily dosing regimen in children with Sickle Celle Disease between 9 months to 11 years of age. Participants will: * Take Hydroxycarbamide twice a day every day for 12 months * Visit the clinic at screening, baseline, 1, 3, 6, 9 and 12 months

This description comes directly from the study's public registry record.

Talk to the study team

Laura Thomas-bourgneuf  ·  + 33 1 49 70 95 83  ·  laura.thomas-bourgneuf@theravia.com

Nesrine Flissi  ·  nesrine.flissi@theravia.com

Always discuss trial participation with your own doctor first.

Locations (6)

Centre Hospitalier Intercommunal CréteilCréteil, FranceRecruiting
GHEF- Site de Marne-la-ValléeJossigny, FranceRecruiting
Hôpital BicêtreLe Kremlin-Bicêtre, FranceRecruiting
Institut d'Hématologie et d'oncologie pédiatrique - IHOPeLyon, FranceActive Not Recruiting
Hôpital Necker-Enfants maladesParis, FranceRecruiting
Centre hospitalier de CayenneCayenne, French GuianaRecruiting

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Source record: clinicaltrials.gov/study/NCT06578507