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Study identifier: NCT06578468 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

End-Tidal Oxygen for Intubation in the Emergency Department

Condition: Critical Illness · Hypoxia · Respiratory Failure  ·  Sponsor: Sydney Local Health District

PhaseNA
Planned participants1400
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Rapid Sequence Intubation (RSI) is a high-risk procedure in the emergency department (ED). Patients are routinely preoxygenated (given supplemental oxygen) prior to RSI to prevent hypoxia during intubation. For many years anaesthetists have used end-tidal oxygen (ETO2) levels to guide the effectiveness of preoxygenation prior to intubation. The ETO2 gives an objective measurement of preoxygenation efficacy. This is currently not available in most EDs. This trial evaluates the use of ETO2 on the rate of hypoxia during intubation for patients in the ED.

This description comes directly from the study's public registry record.

Talk to the study team

Matthew Oliver, MBBS  ·  +61410188680  ·  matthew.oliver@health.nsw.gov.au

Naomi Derrick  ·  +61457240478  ·  naomi.derrick@health.nsw.gov.au

Always discuss trial participation with your own doctor first.

Locations (9)

Hennepin Medical CenterMinneapolis, Minnesota, United StatesNot Yet Recruiting
University of New Mexico Medical CenterAlbuquerque, New Mexico, United StatesNot Yet Recruiting
Lincoln Medical CenterThe Bronx, New York, United StatesRecruiting
Westmead HospitalSydney, New South Wales, AustraliaNot Yet Recruiting
Royal Prince Alfred HospitalSydney, New South Wales, AustraliaRecruiting
Liverpool HospitalSydney, New South Wales, AustraliaNot Yet Recruiting
Northern Beaches HospitalSydney, New South Wales, AustraliaRecruiting
Royal North Shore HospitalSydney, New South Wales, AustraliaNot Yet Recruiting
The Alfred HospitalMelbourne, Victoria, AustraliaNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06578468