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Study identifier: NCT06578182 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

The Effect of ColcHicine on the Incidence of Knee or Hip Replacements

Condition: Osteoarthritis, Knee · Osteoarthritis, Hip  ·  Sponsor: Sint Maartenskliniek

PhasePhase 3
Planned participants1410
Who can joinAll sexes, 45 Years to 80 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to evaluate the effect of treatment with colchicine 0.5mg once daily as compared to placebo in patients with knee or hip osteoarthritis on the incidence of first occurrence of knee or hip replacement. The main question it aims to answer is: Does colchicine lower the number of knee or hip replacements in participants with osteoarthritis? Researchers will compare colchicine to a placebo (a look-alike substance that contains no drug) to see if colchicine works to treat osteoarthritis. Participants will: * take colchicine every day for 3 tot 4.5 years * visit the clinic every year for check-up and tests such as blood samples and x-rays * fill in questionnaires every 3 months

This description comes directly from the study's public registry record.

Talk to the study team

Tim Massa  ·  +31633036353  ·  t.massa@maartenskliniek.nl

Always discuss trial participation with your own doctor first.

Locations (1)

Sint MaartenskliniekNijmegen, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT06578182