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Study identifier: NCT06577532 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study of KRAS Neoantigen mRNA Vaccine (ABO2102) in Patients With KRAS -Mutated Solid Tumors

Condition: Pancreatic Neoplasms · Other Solid Tumors  ·  Sponsor: Ruijin Hospital

PhaseEARLY_Phase 1
Planned participants56
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the safety, immunogenicity, pharmacodynamics, as well as preliminary efficacy of KRAS neoantigen mRNA vaccine (ABO2102) alone and in combination with toripalimab (anti-PD-1 monoclonal antibody) among participants with KRAS-mutated advanced pancreatic cancer and other solid tumors. The trial includes dose escalation (Part I) and dose expansion(Part II) parts.

This description comes directly from the study's public registry record.

Talk to the study team

Xinjing Wang  ·  18817821319  ·  newvista89@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

Ruijin Hospital Affiliated to Shanghai Jiaotong University School of MedicineShanghai, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06577532