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Study identifier: NCT06574880 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

STereotActic Body Radiotherapy and 177Lutetium PSMA in Locally Advanced Prostate Cancer

Condition: Malignant Neoplasm of Prostate · Locally Advanced Prostate Cancer  ·  Sponsor: Angela Y. Jia, MD PhD

PhasePhase 1/Phase 2
Planned participants45
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to is to investigate if it is possible to lower the chance of cancer reoccurrence and also preserve quality of life by using the drug Pluvicto instead of androgen-deprivation therapy to the usual radiation therapy for advanced local prostate cancer. Participants will receive one dose of Pluvicto, followed by radiation about 6 weeks later. Radiation therapy will be completed in 5 treatments over the period of 2 weeks. A second dose of Pluvicto will be given 6 weeks after radiation is complete. Some participants may also receive a third dose of Pluvicto, and this would be given 6 weeks after the second dose of Pluvicto.

This description comes directly from the study's public registry record.

Talk to the study team

Angela Y Jia, MD, PhD  ·  216-844-3262  ·  Angela.Jia@UHhospitals.org

Always discuss trial participation with your own doctor first.

Locations (1)

University Hospitals Cleveland Medical Center Seidman Cancer Center, Case Comprehensive Cancer CenterCleveland, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06574880