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Study identifier: NCT06574269 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study on TLC590 for Managing Postsurgical Pain

Condition: Postsurgical Pain Management  ·  Sponsor: TLC Biopharmaceuticals, Inc.

PhasePhase 2
Planned participants120
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

This Phase 2 open-label trial investigates the pharmacokinetics (PK), pharmacodynamics, and safety profile of TLC590 across various surgical procedures. Researchers aim to determine the maximum tolerated dose (MTD) of TLC590 via Safety Monitoring Committee (SMC). The study evaluates TLC590 in bunionectomy, laparoscopy-assisted open ventral hernia repair, breast augmentation, abdominoplasty, and total knee arthroplasty models. Additionally, it determines the relative bioavailability of TLC590 to ropivacaine injection.

This description comes directly from the study's public registry record.

Talk to the study team

Jack Chang  ·  +886-2-26557377  ·  Jack@tlcbio.com

Always discuss trial participation with your own doctor first.

Locations (2)

First Surgical HospitalBellaire, Texas, United StatesRecruiting
Memorial Hermann VillageHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06574269