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Study identifier: NCT06572514 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

De-escalation Radiation Strategy After NAC in Combination With ICI in LAHNSCC

Condition: Locally Advanced Head and Neck Squamous Cell Carcinoma  ·  Sponsor: Ruijin Hospital

PhasePhase 1/Phase 2
Planned participants20
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is a single-arm exploratory study conducted in LAHNSCC. Eligible patients received two cycles of pembrolizumab immunotherapy in combination with albumin-bound paclitaxel and cisplatin induction chemotherapy, followed by definitive concurrent radiochemotherapy. Three months after the completion of radiotherapy, a follow-up examination was conducted, and salvage surgery or systemic therapy was performed as necessary based on the follow-up results.

This description comes directly from the study's public registry record.

Talk to the study team

Yujie Wang, M.D.  ·  +86 02164370045  ·  wyj12054@rjh.com.cn

Yusheng Gao, M.D.  ·  +86 02164370045  ·  gys11856@rjh.com.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Ruijin Hospital, Shanghai Jiaotong University School of MedicineShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06572514