← Eichor
Study identifier: NCT06572423 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Personalized Ultrafractionated Stereotactic Adaptive Radiotherapy for Palliative Head and Neck Cancer Treatment (PULS-Pal)

Condition: Head and Neck Carcinoma · Localized Head and Neck Carcinoma · Metastatic Head and Neck Carcinoma  ·  Sponsor: Jonsson Comprehensive Cancer Center

PhaseNA
Planned participants43
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This trial tests how well personalized ultra fractionated stereotactic adaptive radiotherapy (PULSAR) works together with HyperArc© radiation treatment planning technology for palliative (holistic pain and symptom control) tumor control in patients with primary or recurrent, localized or metastatic head and neck cancer (HNC) who are ineligible for or decline standard of care treatment. Researchers want to evaluate if using HyperArc and PULSAR together will deliver higher, possibly more effective doses, resulting in better tumor control with the same or fewer side effects than smaller routine doses. PULSAR is a radiation therapy regimen that uses a limited number of fairly large dose pulses while adjusting to specific anatomic and/or biological changes which may occur during the course of the treatment. HyperArc radiation treatment planning technology is a tool that allows for target dose escalation to tumor tissue while maintaining minimal head and neck organs-at-risk doses compared to other radiation treatment planning software. Undergoing PULSAR and HyperArc technology together may be a safe and effective palliative treatment option for patients with HNC.

This description comes directly from the study's public registry record.

Talk to the study team

Mili Santoso  ·  310 267-2153  ·  msantoso@mednet.ucla.edu

Vincent Basehart  ·  3102678954  ·  vbasehart@mednet.ucla.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of California at Los AngelesLos Angeles, California, United StatesRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT06572423