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Study identifier: NCT06570629 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Addressing Unintentional Leakage When Using Nasal CPAP - Study B

Condition: Continuous Positive Airway Pressure · Adverse Effect · Obstructive Sleep Apnea  ·  Sponsor: University of Sao Paulo General Hospital

PhaseNA
Planned participants50
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

Oral unintentional leak is a common side effect of continuous positive airway pressure (CPAP) for obstructive sleep apnea (OSA) treatment. Management of oral unintentional leakage has not been standardized and the effectiveness of potential approaches have not been studied in controlled studies. Higher levels of CPAP are associated with higher leak. In the present study, a sequential approach to control excessive unintentional leak will be tested. In study A, the reduction of therapeutic CPAP level will be tested. In study B, oronasal CPAP will be compared to nasal CPAP with a chinstrap.

This description comes directly from the study's public registry record.

Talk to the study team

Pedro Genta  ·  551126625486  ·  prgenta@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Sleep Laboratory, Heart Institute, Pulmonary Division, Hospital das Clínicas da Universidade de São PauloSão Paulo, Brazil, BrazilRecruiting

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Source record: clinicaltrials.gov/study/NCT06570629