Condition: Diabetes Mellitus · Sponsor: Institut National de la Santé Et de la Recherche Médicale, France
The main objective of the study is to assess the contribution of whole genome sequencing (WGS) coupled with a multidisciplinary conciliation meeting (MCM) on diagnosis of atypical forms of diabetes compared to an in-silico analysis of a panel of validated genes (ISApanel), corresponding to current practice, in a randomized trial. Notably, the questions it aims to answer are: * The feasibility of the WGS coupled with MCM on diagnosis of atypical forms of diabetes, * The contribution of WGS coupled with MCM on number of genetic alterations likely causal of diabetes identified and with a modification in care and support of patients. After inclusion and sampling for genotyping, patients will be followed for 5 years. The target population is 1020 adults with atypical diabetes for whom it is possible to obtain a blood sample.
This description comes directly from the study's public registry record.
Jean-François Gautier · +33 01 49 95 90 20 · jean-francois.gautier@aphp.fr
Always discuss trial participation with your own doctor first.
| University Hospital | Amiens, France | Recruiting |
| University Hospital | Angers, France | Recruiting |
| University Hospital Jean Minjoz | Besançon, France | Recruiting |
| University Hospital Haut Lévêque | Bordeaux, France | Recruiting |
| University Hospital Cavale Blanche | Brest, France | Recruiting |
| Centre Hospitalier Sud Francilien | Corbeil-Essonnes, France | Recruiting |
| University Hospital Bocage | Dijon, France | Recruiting |
| University Hospital Michallon | Grenoble, France | Recruiting |
| Assistance Publique Hôpitaux de Paris, Bicêtre Hospital | Le Kremlin-Bicêtre, France | Not Yet Recruiting |
| University Hospital Louis Pradel | Lyon, France | Recruiting |
| University Hospital Sud | Lyon, France | Recruiting |
| University Hospital Conception | Marseille, France | Recruiting |
+ 14 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06570278