Condition: Non-Small Cell Lung Cancer · Sponsor: AbbVie
Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably. Non-small cell lung cancer (NSCLC) is a solid tumor, a disease in which cancer cells form in the tissues of the lung. The purpose of this study is to assess how safe telisotuzumab vedotin is in adult participants with NSCLC. Change in disease activity and adverse events will be assessed. Telisotuzumab vedotin is an investigational drug being developed for the treatment of NSCLC. Participants will be randomly assigned a treatment of telisotuzumab vedotin in 1 of 3 arms at an 1:1:1 ratio. Each group receives intravenous (IV) infusion of telisotuzumab vedotin at different doses. Approximately 150 adult participants with c-Met overexpressing NSCLC will be enrolled in the study at approximately 80 to 90 sites worldwide. Participants will receive IV telisotuzumab vedotin at 1 of 3 dose regimens as part of a 3 year study duration. There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend regular visits during the study at a hospital or clinic. The effect of the treatment will be checked by medical assessments, blood tests, checking for side effects and completing questionnaires.
This description comes directly from the study's public registry record.
ABBVIE CALL CENTER · 844-663-3742 · abbvieclinicaltrials@abbvie.com
Always discuss trial participation with your own doctor first.
| Ironwood Cancer and Research Center /ID# 276370 | Chandler, Arizona, United States | Recruiting |
| University of Arkansas for Medical Sciences /ID# 272923 | Little Rock, Arkansas, United States | Recruiting |
| Valkyrie Clinical Trials /ID# 271322 | Los Angeles, California, United States | Recruiting |
| Yale New Haven Hospital /ID# 271584 | New Haven, Connecticut, United States | Recruiting |
| Cancer Specialists of North Florida - Jacksonville - AC Skinner Parkway /ID# 270899 | Jacksonville, Florida, United States | Recruiting |
| Ocala Oncology Center /ID# 273697 | Ocala, Florida, United States | Recruiting |
| Memorial Hospital West /ID# 270313 | Pembroke Pines, Florida, United States | Recruiting |
| Comprehensive Hematology Oncology /ID# 270422 | St. Petersburg, Florida, United States | Recruiting |
| Florida Cancer Specialists - North /ID# 271995 | St. Petersburg, Florida, United States | Recruiting |
| Florida Cancer Specialists - East /ID# 271993 | West Palm Beach, Florida, United States | Recruiting |
| University Cancer & Blood Center /ID# 270969 | Athens, Georgia, United States | Recruiting |
| Northwest Georgia Oncology Centers /ID# 275374 | Marietta, Georgia, United States | Recruiting |
+ 68 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06568939