Condition: Consciousness Disorders · Sponsor: Massachusetts General Hospital
Disorders of consciousness (DoC) caused by severe brain injury affect millions of people worldwide each year. A patient's level of consciousness in the intensive care unit (ICU) significantly impacts the recovery from disability and is a primary determinant of family decisions about withdrawal of life-sustaining therapy (WLST). However, reliable assessment of consciousness in the ICU remains elusive. Transcranial magnetic stimulation-electroencephalography (TMS-EEG) is a tool that has shown the best performance in detecting signs of consciousness in patients with chronic DoC. The goals of this prospective, observational study are to demonstrate the diagnostic performance and prognostic utility of TMS-EEG in the ICU setting.
This description comes directly from the study's public registry record.
Brian L. Edlow, MD · 617-724-6352 · bedlow@mgh.harvard.edu
Melanie Boly, MD, PhD · boly@neurology.wisc.edu
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| Massachusetts General Hospital | Boston, Massachusetts, United States | Recruiting |
| UW Health University Hospital | Madison, Wisconsin, United States | Not Yet Recruiting |
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Source record: clinicaltrials.gov/study/NCT06568536