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Study identifier: NCT06567990 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Type 2 DIAbeTes With NAFLD: innOvative Biomarkers of Disease progressioN and clInical outComes

Condition: Metabolic Dysfunction-Associated Liver Disease  ·  Sponsor: Hospices Civils de Lyon

PhaseNA
Planned participants500
Who can joinAll sexes, 40 Years to 80 Years
Healthy volunteersNo

About this study

Type 2 diabetes (T2DM) patients are at high-risk for advanced fibrosis (AF) due to non-alcoholic fatty liver disease (NAFLD), recently renamed Metabolic dysfunction-Associated Liver Disease (MASLD). Thus, patients with T2DM are recognized as a priority target for the screening of MASLD-related advanced fibrosis and a systematic screening for AF is currently recommended in T2DM patients using FIB-4 and liver stiffness measurement (LSM).The main objective of the project is to investigate the ability of baseline non-invasive biomarkers to discriminate patients with a progression of MASLD from patients without progression of MASLD among patients with T2DM and to investigate the association between clinical outcomes related to the natural evolution of MASLD and T2DM and baseline biomarkers.

This description comes directly from the study's public registry record.

Talk to the study team

Cyrielle CAUSSY, Pr  ·  4 78 86 44 48  ·  cyrielle.caussy@chu-lyon.fr

Dominique DELAUNAY, Dr  ·  4 72 11 00 64  ·  Dominique.delaunay@chu-lyon.fr

Always discuss trial participation with your own doctor first.

Locations (4)

Service Endocrinologie, Diabétologie, Maladies Métaboliques et NutritionDijon, FranceRecruiting
Endocrinologie, Diabète et Nutrition in Louis PRADEL HospitalLyon, FranceRecruiting
Clinique d'Endocrinologie, Maladies Métaboliques et Nutrition CIC Endocrino-NutNantes, FranceRecruiting
Service d'Endocrinologie, Diabète et nutritionPierre-Bénite, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT06567990