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Study identifier: NCT06567340 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

StratCare Trial 2: Evaluating the Clinical and Cost-effectiveness of AI-driven Stratified Care for Depression

Condition: Depression  ·  Sponsor: Rotherham Doncaster and South Humber NHS Foundation Trust

PhaseNA
Planned participants1252
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Depression and anxiety are common mental health problems affecting around one in six adults. Treatments include therapy, telephone or group-based activities delivered by therapists. Treatment uses a "stepped care" model where most patients start with very brief treatments. If they remain unwell after this, they access longer and more intensive therapy. This model does not always work, as only one out of two patients fully recover. The researchers have developed an artificial intelligence tool called "StratCare". It is designed to help health services to offer the best available treatment for each patient. StratCare is a computerised system that guides therapists on how to assess new patients. It asks a few questions about their symptoms, personality, and background. The system makes a recommendation about which treatment might be most effective for that person. This is either starting with brief therapy or starting with intensive therapy. The treatments are already used with depression in the National health Service (NHS). The patient can discuss with their therapist and decide whether to accept the recommendation. Otherwise, they can discuss trying other options. Previous research found that StratCare can help more people to recover from depression compared to the usual stepped care model. The researchers will investigate if the StratCare tool works on a large scale in the NHS and if it helps patients in the long-term. The researchers will run a trial involving 1252 partic…

This description comes directly from the study's public registry record.

Talk to the study team

Jonathan Woodward  ·  0114 2222966  ·  jonathan.woodward@sheffield.ac.uk

Jeannie McKie  ·  03000 212456  ·  rdash.research-gov@nhs.net

Always discuss trial participation with your own doctor first.

Locations (10)

Tees, Esk and Wear Valleys NHS Foundation TrustDarlington, Durham, United KingdomRecruiting
Lancashire and South Cumbria NHS Foundation TrustPreston, Lancashire, United KingdomRecruiting
West London NHS TrustSouthall, London, United KingdomRecruiting
Vita Health GroupNottingham, Nottinghamshire, United KingdomRecruiting
Somerset NHS Foundation TrustTaunton, Somerset, United KingdomRecruiting
Rotherham Doncaster and South Humber NHS Foundation TrustDoncaster, South Yorkshire, United KingdomRecruiting
Surrey and Borders Partnership NHS Foundation TrustLeatherhead, Surrey, United KingdomRecruiting
Cheshire and Wirral Partnership NHS Foundation TrustChester, United KingdomRecruiting
Homerton Healthcare NHS Foundation TrustLondon, United KingdomRecruiting
Central and Nort h West London NHS Foundation TrustLondon, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT06567340