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Study identifier: NCT06567301 Synced from ClinicalTrials.gov · July 29, 2026
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Extracorporeal Shockwave Versus Phonophoresis Using Chitosan-Nanoparticles Gel on Functional and Anatomical Changes Detected With Artificial Intelligence Based Texture Analysis Algorithm in Knee Osteoarthritis Patients: A Double Blind Randomized Controlled Trial

Condition: Knee Osteoarthritis · Chitosan Nanoparticles Gel · Artificial Intelligence Texture Analysis Bases Algorithm  ·  Sponsor: Cairo University

PhaseNA
Planned participants120
Who can joinAll sexes, 40 Years to 60 Years
Healthy volunteersNo

About this study

A parallel double blinded randomized controlled clinical trial (RCT) with a 1:1:1 allocation will be conducted in an orthopedic clinic in Cairo and Giza Governments - Egypt. This RCT will evaluate the pain reduction, self-reported functional improvement, physical functional and anatomical improvement following the application of phonophoresis using chitosan-nanoparticles gel, ECSW therapy and traditional exercises compared to each other. The treatment period will last for 4 weeks with a total of (12 sessions/ 3 sessions per week for the application of phonophoresis using chitosan-nanoparticles gel and traditional exercises program) and (5 sessions/ 1 every week for the application of ECSWT). The participants will be assessed at two different time-points (before-after treatment) with a sample size of 40 patients in each group (3 groups)

This description comes directly from the study's public registry record.

Talk to the study team

Athar Tarek Mohamed Fahmy Azab, Master  ·  0201001909236  ·  athartarek29790@gmail.com

Hamdy Mamdouh Amir  ·  0201112831021  ·  athartarek29790@gmail.com

Always discuss trial participation with your own doctor first.

Locations (2)

Physical Therapy College - Cairo UniversityGiza, El Dokki, EgyptRecruiting
Physical therapy college - Cairo UniversityGiza, EL Doqqi, EgyptRecruiting

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Source record: clinicaltrials.gov/study/NCT06567301