Condition: Carcinoma, Non-Small-Cell Lung · Sponsor: The Methodist Hospital Research Institute
This is a Phase I Trial evaluating the safety of the dietary supplement honokiol for lung cancer chemoprevention. Female or male patients aged 18 years, or older, with early stage lung cancer who have been scheduled for curative surgery will be eligible for participation in the study. The study will only enroll patients with stage I lung cancers less than 4 cm, given the recent approval of neoadjuvant chemotherapy and nivolumab for stage IB tumors \> 4 cm. Approximately, 15 patients will be enrolled in the study. They will take the study drug, honokiol, for 2 weeks prior to the surgery. The primary endpoint will be the Maximum Tolerated Dose (MTD) of honokiol.
This description comes directly from the study's public registry record.
Jun Zhang, MD · 713-441-6698 · jzhang22@houstonmethodist.org
Always discuss trial participation with your own doctor first.
| Houston Methodist Neal Cancer Center | Houston, Texas, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06566443