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Study identifier: NCT06565741 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

EEAP Using Moses 2.0 Technology vs the Thulium Fiber Laser in Medium-Large Prostates

Condition: Prostatic Hyperplasia · Surgery · Endoscopic Anatomical Enucleation of the Prostate (EEAP)  ·  Sponsor: Fundacio Puigvert

PhaseNA
Planned participants120
Who can joinMale, 40 Years to 90 Years
Healthy volunteersNo

About this study

Introduction: Endoscopic anatomical enucleation of the prostate (EEAP) with lasers has emerged as an effective and less invasive surgical option compared to traditional methods. Among the various available laser options, Holmium laser and Thulium Fiber laser have stood out as two prominent approaches for performing endoscopic prostate enucleation. These technologies have 3 showcased their effectiveness in ablating prostatic tissue and improving urinary symptoms. Nevertheless, differences in their physical properties and modes of action may impact their success rates and clinical outcomes. In our institution it is standard practice to use one laser or the other according to their availability in the operating room. Primary Objective: To demonstrate the superiority of MoLEP over ThuFLEP in terms of enucleation efficiency. Secondary Objectives: a) To demonstrate the non-inferiority of MoLEP compared to ThuFLEP in terms of perioperative bleeding. b) To demonstrate the non-inferiority of MoLEP compared to ThuFLEP in terms of postoperative hospital stay. c) To demonstrate the non-inferiority of ThuFLEP compared to ThuFLEP in terms of perioperative complications. d) To demonstrate the non-inferiority of MoLEP compared to ThuFLEP in terms of improvement in urinary symptoms. e) To demonstrate the non-inferiority of MoLEP compared to ThuFLEP in terms of improvement in flowmetric variables. Study Type: Prospective, randomized, non-blind, multicentric clinical trial. Intervention:…

This description comes directly from the study's public registry record.

Talk to the study team

Ivan Schwartzmann Jochamowitz, MD  ·  0034934169700  ·  ischwartzm@fundacio-puigvert.es

Silvia Mateu, MD  ·  0034934169700  ·  smateu@fundacio-puigvert.es

Always discuss trial participation with your own doctor first.

Locations (3)

Fundacio PuigvertBarcelona, BARCELONA, SpainRecruiting
Clinic Hospital of BarcelonaBarcelona, BARCELONA, SpainRecruiting
Hospital Univesitari de BellvitgeL'Hospitalet de Llobregat, BARCELONA, SpainRecruiting

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Source record: clinicaltrials.gov/study/NCT06565741