Condition: Colorectal Cancer · Sponsor: Takeda
High blood pressure (hypertension) is a known side effect of the treatment with fruquintinib. Current research does not provide a clear answer whether minority groups such as Black/African American and/or Hispanic/Latino with refractory metastatic colorectal cancer (mCRC) have a bigger risk of higher blood pressure after treatment with fruquintinib. The main aim of this study is to learn how often adults of a minority group experience hypertension after they have been treated with fruquintinib for refractory mCRC. Other aims are to learn how safe fruquintinib is and how well it is tolerated by participants. Participants will receive fruquintinib in 4-week treatment cycles until their condition worsens, they do no longer tolerate the treatment or stop the treatment for other reasons. After the last treatment, participants will be checked upon every 3 months until study completion.
This description comes directly from the study's public registry record.
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| Central Alabama Research | Birmingham, Alabama, United States | Recruiting |
| University of Alabama at Birmingham | Birmingham, Alabama, United States | Recruiting |
| Ironwood Cancer and Research Centers | Chandler, Arizona, United States | Recruiting |
| University of Arizona | Tucson, Arizona, United States | Recruiting |
| University of California San Diego | La Jolla, California, United States | Recruiting |
| University of Southern California | Los Angeles, California, United States | Recruiting |
| PIH Health Whittier Hospital | Whittier, California, United States | Recruiting |
| Christiana Care Health Services | Newark, Delaware, United States | Recruiting |
| University of Florida | Gainesville, Florida, United States | Completed |
| University of Miami | Miami, Florida, United States | Withdrawn |
| Baptist Health - Miami Cancer Institute | Miami, Florida, United States | Withdrawn |
| Emory University | Atlanta, Georgia, United States | Recruiting |
+ 33 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06562543