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Study identifier: NCT06562400 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Searching for Novel Therapeutic Approaches in Migraine Patients Resistant to Treatments

Condition: Migraine Disorders · Chronic Migraine · Episodic Migraine  ·  Sponsor: IRCCS National Neurological Institute "C. Mondino" Foundation

PhaseN/A
Planned participants45
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

Primary working hypothesis is that NON-responders to mAbs bear a dysfunction of the endocannabidiome system (eCBome), as suggested by pre-clinical and clinical data by our group. They will be identified as patients showing a reduction of monthly migraine days \< 50% after three months of treatment. The clinical, biochemical and neurofunctional impact of novel therapeutic approaches expected to interfere with eCBome will be evaluated in NON-responder patients

This description comes directly from the study's public registry record.

Talk to the study team

Roberto De Icco  ·  00390382380425  ·  roberto.deicco@mondino.it

Cinzia Fattore  ·  00390382380385  ·  cinzia.fattore@mondino.it

Always discuss trial participation with your own doctor first.

Locations (1)

Headache Science & Neurorehabilitation UnitPavia, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT06562400