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Study identifier: NCT06562192 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers

Condition: Pancreatic Ductal Adenocarcinoma · Non-small Cell Lung Cancer · HR+/HER2- Ductal and Lobular Breast Cancer  ·  Sponsor: Novartis Pharmaceuticals

PhasePhase 1
Planned participants162
Who can joinAll sexes, 18 Years to 100 Years
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the safety, tolerability, dosimetry and preliminary efficacy of \[177Lu\]Lu-NNS309 and the safety and imaging properties of \[68Ga\]Ga-NNS309 in patients aged ≥ 18 years with locally advanced or metastatic pancreatic ductal adenocarcinoma (PDAC), non-small cell lung cancer (NSCLC), HR+/HER2- ductal and lobular breast cancer (BC), triple negative breast cancer (TNBC) and colorectal cancer (CRC).

This description comes directly from the study's public registry record.

Talk to the study team

Novartis Pharmaceuticals  ·  1-888-669-6682  ·  novartis.email@novartis.com

Novartis Pharmaceuticals  ·  +41613241111  ·  novartis.email@novartis.com

Always discuss trial participation with your own doctor first.

Locations (29)

Uni of Alabama at BirminghamBirmingham, Alabama, United StatesRecruiting
University of California LALos Angeles, California, United StatesRecruiting
Stanford University Medical CenterPalo Alto, California, United StatesRecruiting
Mayo Clinic JacksonvilleJacksonville, Florida, United StatesRecruiting
Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting
BAMF HealthGrand Rapids, Michigan, United StatesRecruiting
Mayo Clinic RochesterRochester, Minnesota, United StatesRecruiting
Uni Of TX MD Anderson Cancer CntrHouston, Texas, United StatesRecruiting
University Of WashingtonSeattle, Washington, United StatesRecruiting
Novartis Investigative SiteBrussels, BelgiumRecruiting
Novartis Investigative SiteToronto, Ontario, CanadaRecruiting
Novartis Investigative SiteMontreal, Quebec, CanadaRecruiting

+ 17 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06562192