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Study identifier: NCT06559891 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension

Condition: Hypertension  ·  Sponsor: SoniVie Inc.

PhaseNA
Planned participants261
Who can joinAll sexes, 22 Years to 75 Years
Healthy volunteersNo

About this study

The primary objective of the THRIVE Pivotal study is to demonstrate the adjunctive effectiveness and the safety of the TIVUS system in: 1. subjects with uncontrolled hypertension (HTN) receiving 0 - 2 anti-hypertensive drugs of different classes in whom the anti-hypertensive medications will be stopped for a 4-week wash-out period before RDN/Sham procedure and during 2 months after procedure. 2. subjects with controlled hypertension receiving 1 - 2 anti-hypertensive drugs of different classes and who accept to be off-medications for a 4-week wash-out period before RDN/Sham procedure and 2 months after the procedure

This description comes directly from the study's public registry record.

Talk to the study team

Lisa Melchior  ·  651-324-4931  ·  lisa.melchior@bsci.com

Janelle Noble  ·  612-598-4368  ·  janelle.noble@bsci.com

Always discuss trial participation with your own doctor first.

Locations (50)

Cardiology, PCBirmingham, Alabama, United StatesRecruiting
Honor Health Research InstitueScottsdale, Arizona, United StatesRecruiting
St. Bernard's Medical CenterJonesboro, Arkansas, United StatesRecruiting
Arkansas Heart HospitalLittle Rock, Arkansas, United StatesRecruiting
Cedar-Sinai Medical CenterLos Angeles, California, United StatesRecruiting
Stanford UniversityPalo Alto, California, United StatesRecruiting
BridgeportBridgeport, Connecticut, United StatesRecruiting
Ascension- Sacred HeartPensecola, Florida, United StatesRecruiting
University of South FloridaTampa, Florida, United StatesRecruiting
Ascension Alexian BrothersElk Grove Village, Illinois, United StatesRecruiting
St. John's Prairie HeartSpringfield, Illinois, United StatesRecruiting
Southern Illinois University, School of MedicineSpringfield, Illinois, United StatesRecruiting

+ 38 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06559891