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Study identifier: NCT06557460 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Phase IIb Randomized, Multicenter Trial of Subretinal CPCB-RPE1 in Advanced Dry AMD (Geographic Atrophy)

Condition: Dry Age-related Macular Degeneration · Geographic Atrophy  ·  Sponsor: Regenerative Patch Technologies, LLC

PhasePhase 2
Planned participants24
Who can joinAll sexes, 55 Years to 90 Years
Healthy volunteersNo

About this study

This is a Phase IIb randomized, clinical trial designed to assess the safety and efficacy of unilateral implantation of the CPCB-RPE1 implant in subjects with geographic atrophy involving the fovea. Up to 6 surgical implantation sites will deliver the CPCB-RPE1 in this Phase IIb clinical trial. Additional study sites may serve as referral or follow-up sites. Twenty-four (24) subjects will participate in the trial and will be randomized 3:1 to one of 2 groups: * The treatment group receiving the CPCB-RPE1 implant (up to 18 subjects). * The control group receiving a simulated "sham" implantation procedure (up to 6 subjects)

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Research  ·  833-734-3678  ·  clinicaltrials@regenerativepatch.com

Always discuss trial participation with your own doctor first.

Locations (5)

Retina-Vitreous Associates Medical GroupBeverly Hills, California, United StatesRecruiting
Retina Associates of Southern CaliforniaHuntington Beach, California, United StatesRecruiting
USC - KeckLos Angeles, California, United StatesRecruiting
University RetinaLemont, Illinois, United StatesRecruiting
Retina Consultants of TexasThe Woodlands, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06557460