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Study identifier: NCT06555757 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Utilising AI Analysis of Sounds To prEdict heaRt failurE decOmpensation

Condition: Heart Failure  ·  Sponsor: Cambridge University Hospitals NHS Foundation Trust

PhaseN/A
Planned participants250
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Heart failure impacts more than 2% of people in the UK (United Kingdom) and leads to about 5% of emergency hospital visits. Patients might have slowly worsening symptoms or suddenly face acute decompensated heart failure (ADHF), marked by intense difficulty in breathing due to fast-developing lung congestion. This is a serious emergency requiring in-hospital treatment and monitoring. Once stable, patients usually have a phase where symptoms remain constant. But as time goes on, those with heart failure often face more frequent and prolonged episodes of ADHF. Fluid build-up (pulmonary congestion) in the lungs is a key issue in heart failure, and catching it early helps avoid unexpected hospital stays. Spotting these early signs outside the hospital can be tough, as symptoms aren't always clear. Study investigators are working on a new, non-invasive way to identify these early signs using AI (artificial intelligence) to analyse subtle changes in a patient's voice, cough, and breathing sounds. This tool will act as an early warning for patients and their heart care teams, allowing quicker treatment. This could make heart failure episodes less severe and reduce the need for hospital visits. This research has two parts. First, a small pilot trial with up to 50 patients. The findings will guide and inform a larger study involving up to 200 patients. From this larger study, investigators will develop the final version of the AI algorithm. The results from the Part A and Part B of …

This description comes directly from the study's public registry record.

Talk to the study team

Erdem Demir  ·  +44 1223 256621  ·  erdem.demir1@nhs.net

Heike Templin  ·  +44 1223 250874  ·  heike.templin@nhs.net

Always discuss trial participation with your own doctor first.

Locations (1)

Cambridge University Hospitals NHS Foundation TrustCambridge, Cambridgeshire, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT06555757