Condition: Oropharynx Cancer · Sponsor: Georgetown University
The goal of this clinical trial is to learn whether for intermediate-risk patients who have undergone Transoral Robotic Surgery for HPV/p16(+) oropharyngeal cancer and have minimal smoking history, whether these patients can be treated with a lower-than standard dose, with omission of the primary site in the oropharynx. The main questions it aims to answer are: Does radiotherapy site and dose-de-escalation lead to similar outcomes compared to historical data on tumor control in patients who are treated with standard radiation doses and treatment fields? Participants will: Undergo treatment with a lower than standard radiation dose (50Gy in 25 fractions, with either Intensity Modulated Radiation Therapy (IMRT) or proton beam therapy) and to a smaller than standard radiation field (to the neck only, excluding the original site of tumor in the oropharynx)
This description comes directly from the study's public registry record.
Peter Ahn, MD · (202) 444-4036 · Peter.H.Ahn@gunet.georgetown.edu
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| Medstar Georgetown University Hospital | Washington D.C., District of Columbia, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06554158