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Study identifier: NCT06554041 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Soft Tissue Response to Different Restorative Materials Used in Implant Dentistry

Condition: Edentulous Alveolar Ridge · Peri-Implantitis · Peri-implant Mucositis  ·  Sponsor: Harvard Medical School (HMS and HSDM)

PhaseNA
Planned participants40
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

The goal of this clinical trial is to learn how different materials used in dental implants affect the surrounding gum tissue in adults who need dental implants. The main questions it aims to answer are: How do different materials (titanium, PEEK, zirconia, and lithium disilicate) affect inflammation around dental implants? What changes occur in inflammation markers in the gum tissue after 3 and 6 months? Researchers will compare the different materials to see which one causes the least amount of inflammation. Participants will: Receive dental implants made from different materials. Have samples of fluid from around their implants collected for analysis at 3 and 6 months. Undergo regular dental check-ups to measure gum health, such as bleeding and pocket depth around the implants.

This description comes directly from the study's public registry record.

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Contact details are listed per location below or on the registry record.

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Locations (1)

VIC ClinicVilnius, LithuaniaRecruiting

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Source record: clinicaltrials.gov/study/NCT06554041