Condition: Hereditary Spastic Paraplegia · Primary Lateral Sclerosis · SPG4 · Sponsor: Boston Children's Hospital
The Spastic Paraplegia - Centers of Excellence Research Network (SP-CERN) is a collaborative research consortium dedicated to advancing the understanding, diagnosis, and treatment of hereditary spastic paraplegia (HSP) and primary lateral sclerosis (PLS). Aims of the consortium are to a) perform natural history studies of HSP subtypes, b) discover and validate biomarkers and clinician- and patient-reported outcome measures, c) uncover HSP's molecular pathophysiology and develop rational therapeutic targets, and d) perform sufficiently powered clinical trials. The current pilot study is aimed at enrolling 100 individuals with hereditary spastic paraplegia type 4 (SPG4) or hereditary spastic paraplegia type 5A (SPG5A).
This description comes directly from the study's public registry record.
Darius Ebrahimi-Fakhari, MD, PhD. · 617-355-0097 · hsp.research@childrens.harvard.edu
Nicole Battaglia, BS. · 617-919-7450 · hsp.research@childrens.harvard.edu
Always discuss trial participation with your own doctor first.
| University of Miami Miller School of Medicine | Miami, Florida, United States | Not Yet Recruiting |
| University of Iowa Carver College of Medicine | Iowa City, Iowa, United States | Not Yet Recruiting |
| Boston Children's Hospital | Boston, Massachusetts, United States | Recruiting |
| Massachusetts General Hospital | Boston, Massachusetts, United States | Not Yet Recruiting |
| University of Michigan School of Medicine | Ann Arbor, Michigan, United States | Not Yet Recruiting |
| Columbia University - Irving Medical Center | New York, New York, United States | Not Yet Recruiting |
| Cincinnati Children's Hospital Medical Center | Cincinnati, Ohio, United States | Not Yet Recruiting |
| Scottish Rite for Children | Dallas, Texas, United States | Not Yet Recruiting |
| Texas Children's Hospital | Houston, Texas, United States | Not Yet Recruiting |
| Seattle Children's Hospital | Seattle, Washington, United States | Not Yet Recruiting |
| University of Washington School of Medicine | Seattle, Washington, United States | Not Yet Recruiting |
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Source record: clinicaltrials.gov/study/NCT06553976