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Study identifier: NCT06553872 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Phase 2 Open Label Randomized Study of Pirtobrutinib and Brexucabtagene Autoleucel in R/R MCL

Condition: Mantle Cell Lymphoma  ·  Sponsor: H. Lee Moffitt Cancer Center and Research Institute

PhasePhase 2
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a phase 2, open-label, randomized, multicenter clinical trial in patients with relapsed/refractory mantle cell lymphoma (R/R MCL) who meet the criteria for standard-of-care FDA label for CD19 CAR T-cell therapy with brexucabtagene autoleucel (brexu-cel).

This description comes directly from the study's public registry record.

Talk to the study team

Ruthie Chae  ·  813-745-3425  ·  ICETtrials@moffitt.org

Always discuss trial participation with your own doctor first.

Locations (3)

Stanford Cancer CenterStanford, California, United StatesNot Yet Recruiting
Univ of Miami - Sylvester Comprehensive Cancer CenterMiami, Florida, United StatesRecruiting
Moffitt Cancer CenterTampa, Florida, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06553872