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Study identifier: NCT06551662 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

DCB vs. DES in Bifurcation Coronary Lesions

Condition: Coronary Artery Disease · DCB  ·  Sponsor: Fondazione Ricerca e Innovazione Cardiovascolare ETS

PhaseNA
Planned participants321
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is an investigator-driven prospective, multicentric, international, randomized clinical study, in an open-label randomized fashion, where patients with bifurcation coronary artery disease (Medina: 111,101,011,001) in vessels with diameter \>2.0 (visual estimation) and with a clinical indication to PCI, will be enrolled. After successful predilatation (with any tool deemed useful), patients will be randomized 1:1:1 to SCB, PCB or standard treatment with DES for bifurcation native vessel disease. All patients with a clinical indication for PCI, both stable coronary artery disease and acute coronary syndrome, will be enrolled. Before participating all the candidates will be clearly informed about the study, including the possible risks and benefits, and will be asked to provide a written informed consent. Subjects will be instructed that may not meet the general criteria for inclusion or the angiographic criteria, or that may have at least one exclusion criteria, and then be excluded from the study (screening failure), even after informed consent is obtained. Consecutive patients who meet at least one of the inclusion criteria and none of the exclusion criteria, will participate to the study. After randomization, the procedure will consist in standard coronary angioplasty following international guidelines/consensus documents and as per local practice. If the patient has been randomized to SCB or PCB, it is mandatory to adequately prepare the lesion.

This description comes directly from the study's public registry record.

Talk to the study team

Bernardo Cortese  ·  504827636  ·  bcortese@gmail.com

Wojciech Wańha  ·  504827636  ·  wojciech.wanha@gmail.com

Always discuss trial participation with your own doctor first.

Locations (17)

Fondazione Ricerca e Innovazione CardiovascolareMilan, ItalyNot Yet Recruiting
First Department of Cardiology, Medical University of Gdansk, Gdansk, PolandGdansk, PolandNot Yet Recruiting
Department of Cardiology and Structural Heart Diseases, Medical University of Silesia, Katowice, PolandKatowice, PolandNot Yet Recruiting
Department of Interventional Cardiology, Institute of Cardiology, Jagiellonian University Medical College, Kraków, PolandKrakow, PolandNot Yet Recruiting
Second Department of Cardiology, Jagiellonian University Medical College, Krakow, PolandKrakow, PolandNot Yet Recruiting
Department of Cardiology, Copper Health Centre (MCZ)Lubin, PolandNot Yet Recruiting
Clinical Department of Interventional Cardiology, Medical University of LublinLublin, PolandNot Yet Recruiting
Department of Cardiology, Poznan University of Medical SciencesPoznan, PolandNot Yet Recruiting
Department of Cardiology, The Ministry of Internal Affairs and Administration Hospital, RzeszowRzeszów, PolandNot Yet Recruiting
Department of Cardiology and Internal Diseases, Military Institute of MedicineWarsaw, PolandNot Yet Recruiting
Department of Invasive Cardiology, Centre of Postgraduate Medical Education, Central Clinical Hospital of the Ministry of Interior and AdministrationWarsaw, PolandNot Yet Recruiting
Department of CardiologyWałbrzych, PolandNot Yet Recruiting

+ 5 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06551662